Cubeb Essential Oil (Piper cubeba)
Overview
Cubeb may also be referred to as Cubeb or tailed pepper. It is typically processed using steam distilled as a method for extracting oil from the berries.
Summary
Cubeb Essential Oil is also referred to asJava Pepper Essential Oil.
Comprised primarily of sesquiterpenes and sesquiterpenols, Cubeb Essential Oil is a beautiful essential oil to try for respiratory issues, pain relief, and digestive complaints. See the Uses section below for more information on the benefits of Cubeb Essential Oil.

Essential Facts
- Aroma Description: Cubeb Essential Oil smells warm, sweet and slightly peppery.
- Common Name(s): Cubeb or tailed pepper
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Synonyms(s) for Piper cubeba: Cubeba cubeba, Cubeba officinalis, Cubeba pipereta
- Botanical Family: Piperaceae
- Botanical Genus: Piper
- Major Compounds: Sabinene, Cubebol, a-Copaene, B-Cubebene, Delta-Cadinene, a-Cubebene, a-Pinene, Gamma-Humulene, (+)-Limonene, (-)-allo-Aromadendrene, Gamma-Muurolene, (Z)-Calamene, B-Caryophyllene
- Perfumery Note: Middle - Base
- Consistency: Medium
- Strength of Initial Aroma: Light - Medium
- Color: Clear to Pale Yellow
- Indigenous Country: Middle - Base
- Processing Methods: Steam Distilled
- Part Typically Used: Berries
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Vegan
Essential Details
Benefits & Uses
May be benefitial for addressing the following ailments:
Bodily Congestion
Bronchia
Bronchitis
Coughs
Cystitis
Flatulence
Indigestion
Sinusitis
Therapeutic Benefits of Cubeb:
Cautions & Safety
Cautions when using Cubeb:
Tisserand and Young recommend a dermal maximum of 7.5%. Reading Tisserand and Young's full profile is recommended. [Robert Tisserand and Rodney Young, Essential Oil Safety (Second Edition. United Kingdom: Churchill Livingstone Elsevier, 2014), 263.]
Safety Precautions for Cubeb:
Do not take any oils internally and do not apply undiluted essential oils, absolutes, CO2s or other concentrated essences onto the skin without advanced essential oil knowledge or consultation from a qualified aromatherapy practitioner. If you are pregnant, epileptic, have liver damage, have cancer, or have any other medical problem, use oils only under the proper guidance of a qualified aromatherapy practitioner. Use extreme caution when using oils with children and be sure to first read the recommended dilution ratios for children. Consult a qualified aromatherapy practitioner before using oils with children, the elderly, if you have medical issues or are taking medications. For in-depth information on oil safety issues, read Essential Oil Safety by Robert Tisserand and Rodney Young.
Articles
Cubeb Articles or Publications:
- PubMed: Anticancer activity studies of cubebin isolated from Piper cubeba and its synthetic derivatives.
- PubMed: Evaluation of lignan (-)-cubebin extracted from Piper cubeba on human colon adenocarcinoma cells (HT29).
- PubMed: Cytotoxic activity of Piper cubeba extract in breast cancer cell lines.
- PubMed: Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model.
- PubMed: Biological activities of Zingiber officinale (Zingiberaceae) and Piper cubeba (Piperaceae) essential oils against pulse beetle, Callosobruchus chinensis (Coleoptera: Bruchidae).
- PubMed: In vitro antiparasitic activity and chemical composition of the essential oil obtained from the fruits of Piper cubeba.
- PubMed: Variation in manuka oil lure efficacy for capturing Xyleborus glabratus (Coleoptera: Curculionidae: Scolytinae), and cubeb oil as an alternative attractant.
- PubMed: A comparative study of the modulatory effects of (-)-cubebin on the mutagenicity/recombinogenicity induced by different chemical agents.
- PubMed: The lignan (-)-cubebin inhibits vascular contraction and induces relaxation via nitric oxide activation in isolated rat aorta.
- PubMed: Mutagenicity and antimutagenicity of (-)-hinokinin a trypanosomicidal compound measured by Salmonella microsome and comet assays.
- PubMed: Nephroprotective effect of Kabab chini (Piper cubeba) in gentamycin-induced nephrotoxicity.
- PubMed: Screening of immunomodulatory activity of total and protein extracts of some Moroccan medicinal plants.
- PubMed: Identification of ambiguous cubeb fruit by DART-MS-based fingerprinting combined with principal component analysis.
- PubMed: Essential and toxic elements in three Pakistan's medicinal fruits (Punica granatum, Ziziphus jujuba and Piper cubeba) analysed by INAA.
- PubMed: In vitro efficacy of the essential oil of Piper cubeba L. (Piperaceae) against Schistosoma mansoni.
- PubMed: Radical scavenging ability of some compounds isolated from Piper cubeba towards free radicals.
- PubMed: Was the famous astronomer Copernicus also a nephrologist.
- PubMed: The effect of the dibenzylbutyrolactolic lignan (-)-cubebin on doxorubicin mutagenicity and recombinogenicity in wing somatic cells of Drosophila melanogaster.
- PubMed: Effect of the dibenzylbutyrolactone lignan (-)-hinokinin on doxorubicin and methyl methanesulfonate clastogenicity in V79 Chinese hamster lung fibroblasts.
- PubMed: Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh.
- PubMed: Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties.
- PubMed: Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth?
- PubMed: Evaluation of piper cubeba extract, (-)-cubebin and its semi-synthetic derivatives against oral pathogens.
- PubMed: (-)-Hinokinin causes antigenotoxicity but not genotoxicity in peripheral blood of Wistar rats.
- PubMed: Effect of some medicinal plants on plasma antioxidant system and lipid levels in rats.
- PubMed: Metabolite-cytochrome P450 complex formation by methylenedioxyphenyl lignans of Piper cubeba: mechanism-based inhibition.
- PubMed: Potent CYP3A4 inhibitory constituents of Piper cubeba.
- PubMed: Enzymatic and non-enzymatic antioxidants in selected Piper species.
- PubMed: Investigations of anti-inflammatory and antinociceptive activities of Piper cubeba, Physalis angulata and Rosa hybrida.
- PubMed: Inhibitory effects of sudanese medicinal plant extracts on hepatitis C virus (HCV) protease.
- PubMed: [Constituents of Aristolochia triangularis].
- PubMed: Comparison of vegetative anatomy of piperales. I. Juvenile xylem of twigs.
- PubMed: The occurrence of mature fruits of Piper cubeba in recently imported cubeb.
- PubMed: The problem of foreign botanicals.